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KMID : 0032220230350030205
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Annals of Dermatology
2023 Volume.35 No. 3 p.205 ~ p.216
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Guidelines for the Management of Patients with Alopecia Areata in Korea: Part II Systemic Treatment
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Park Hyun-Sun
Kim Jung-Eun
Choi Jee-Woong
Kim Do-Young
Jang Yong-Hyun
Lee Young
Jeon Jie-Hyun
Shin Hyun-Tae
Kim Min-Sung
Shin Jung-Won
Cho Sung-Bin
Lew Bark-Lynn
Choi Gwang-Seong
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Abstract
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Background: Alopecia areata (AA) is a chronic disease with an unpredictable course and can have a severe psychological impact on an individual.
Objective: To provide evidence and consensus-based statements regarding the treatment of patients with AA in Korea.
Methods: We searched for relevant studies from inception to May 2021 regarding the sys- temic treatment of AA. Evidence-based recommendations were also prepared. The evidence for each statement was graded and classified according to the strength of the recommenda- tions. Hair experts from the Korean Hair Research Society (KHRS) voted on the statement, and an agreement of 75% or greater was considered as having reached consensus.
Results: Current evidence supports the efficacy of systemic corticosteroids, oral cyclospo- rine monotherapy or combination with systemic corticosteroids, and oral Janus kinase inhibitors in severe AA patients. Systemic steroids may be considered for pediatric patients with severe AA. A consensus was achieved in three out of nine (33.3%), and one out of three (33.3%) statements pertaining to systemic treatment in adult and pediatric AA, respectively.
Conclusion: The present study produced up-to-date, evidence-based treatment guidelines for AA associated with the consensus obtained by experts based on the Korean healthcare system.
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KEYWORD
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Alopecia areata, Guideline, Korea, Systemic, Therapeutics, Treatment
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